Targeting a cure

Our mission is to process and harmonize Alzheimer’s Disease genetic and genomic data to facilitate and expedite gene discovery and drug target identification.

Data Submission

NIAGADS guidelines and templates for data contribution to GCAD for harmonization with the Alzheimer’s Disease Sequencing Project dataset.

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Raw Data AnalysisReadyData Data Processing VariantAnnotation QualityControl

From raw to analysis-ready data

Whole-genome and whole-exome sequencing data are processed into CRAMs, gVCFs and then joint called into project level VCFs.

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Collaborating with researchers around the world

GCAD is facilitating collaborations between cohorts and researchers studying neurodegenerative diseases from all over the world.

See our collaborators map

Latest News

  • Attending ASHG 2025? See Us in Action!
    Posted on 10/14/2025

    Are you attending ASHG 2025 this week, 10/14/25-10/18/25, in Boston, MA, USA? The NIAGADS and GCAD team will be there presenting our work and in Booth 1345. See a schedule of where you can connect with our team below: Activity Type Wednesday, 10/15/25 Thursday, 10/16/25 Friday, 10/17/25 Talk Genomic Frontiers…

  • NIH Seeks Public Input on Responsible Development of Innovative AI Tools
    Posted on 6/4/2025

    NIH is committed to advancing novel AI approaches that have the potential to accelerate research and improve the health of the public. As such, NIH is seeking input from the public on how to develop and share new generative AI tools while maintaining the highest privacy protections for biomedical research…

  • Join NIH “Community” Days to Learn About GDS Policy Updates Effective 1/25/25
    Posted on 12/18/2024

    The National Institutes of Health (NIH) will be holding “Community Days” on: Registration is required. Please use the links above to register for the day you plan to attend. ASL will be provided. Who Should Attend: All researchers and their institutional officials who have access to or are planning to…