Targeting a cure

Our mission is to process and harmonize Alzheimer’s Disease genetic and genomic data to facilitate and expedite gene discovery and drug target identification.

Raw Data AnalysisReadyData Data Processing VariantAnnotation QualityControl

From raw to analysis-ready data

Whole-genome and whole-exome sequencing data are processed into CRAMs, gVCFs and then joint called into project level VCFs.

Collaborating with researchers around the world

GCAD is facilitating collaborations between cohorts and researchers studying neurodegenerative diseases from all over the world.

Latest News

  • Working from home? Check out new genetics data for Alzheimer’s disease research!

    The NIA is excited to announce the release of the latest genomics data set from the Alzheimer’s Disease Sequencing Project (ADSP). The NIA Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) is a vital tool as we seek to better understand genes that increase risk for — or protection from — AD/ADRD. Researchers can now access […]

  • NIAGADS DSS Releases 20K Whole Exomes

    NIAGADS is pleased to announce the release of 19,922 whole exomes called on GRCh38 through the Data Sharing Service (DSS). Nine different studies contributed to the release, including 10,088 ADSP Discovery Case Control WES samples, 3,144 ADGC African American WES samples, 75 Brkanac Families WES samples, 346 Corticobasal degeneration WES…

  • Event Recap: The Alzheimer’s Disease Genetics Consortium (ADGC) 10-Year Symposium

    Last month, on November 12 and 13, the Alzheimer’s Disease Genetics Consortium (ADGC) 10-Year Symposium took place at the Inn at Penn in Philadelphia, PA. The event was sponsored by the Perelman School of Medicine and the Department of Pathology and Laboratory Medicine, and it was organized by ADGC, Penn Neurodegeneration Genomics Center (PNGC) and […]